SCHEMBL25828186

SCHEMBL25828186

O=C(c1ccccc1)c1c(OCC(=O)N(CCO)CCO)cc(OCC(=O)N(CCO)CCO)c2sc3ccccc3c(=O)c12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 2/20 0.37
NSD2 O96028 1/20 0.37
LMNA P02545 2/20 0.36
HPGD P15428 1/20 0.36
MAOA P21397 8/20 0.35
MAOB P27338 8/20 0.35
POLB P06746 3/20 0.35
ABCB11 O95342 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
SLC6A2 P23975 1/20 0.35
APEX1 P27695 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4537591 0.80 POLB (0.38) RAD52NSD2LMNAHPGDMAOA
SCHEMBL25828115 0.79 POLB (0.37) RAD52NSD2LMNAHPGDMAOA
SCHEMBL25828107 0.79 POLB (0.43) LMNAHPGDMAOAMAOBPOLB
SCHEMBL25556853 0.74 TSHR (0.42) RAD52NSD2LMNAHPGDMAOA
SCHEMBL25828113 0.73 ALDH1A1 (0.39) LMNAHPGDMAOAMAOBPOLB
SCHEMBL2385517 0.73 KDM4E (0.52) RAD52LMNAHPGDMAOAMAOB
SCHEMBL4562611 0.70 TOP2A (0.31) RAD52NSD2LMNAHPGDPOLB
SCHEMBL25828116 0.69 POLB (0.61) LMNAHPGDPOLBCYP1A2CYP2D6
SCHEMBL6491145 0.68 PTPN1 (0.47) RAD52NSD2LMNAHPGDPOLB
SCHEMBL8064925 0.68 ROCK2 (0.42) RAD52NSD2HPGDMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023180075-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-28 WO disclosed
EP-4249518-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-27 EP disclosed
WO-2023126223-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-06 WO disclosed
EP-4206183-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-05 EP disclosed