Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395905 | 0.92 | ALDH1A1 (0.46) | ALDH1A1HCAR2TDP1POLBAPEX1 | |
| SCHEMBL4170802 | 0.88 | ALDH1A1 (0.53) | ALDH1A1HCAR2TDP1POLBLMNA | |
| SCHEMBL28268541 | 0.88 | TSHR (0.57) | ALDH1A1HCAR2TDP1POLBAPEX1 | |
| SCHEMBL9638004 | 0.88 | TSHR (0.57) | ALDH1A1HCAR2TDP1POLBAPEX1 | |
| SCHEMBL7571673 | 0.86 | THRB (0.46) | ALDH1A1HCAR2TDP1POLBAPEX1 | |
| SCHEMBL7852013 | 0.85 | TSHR (0.55) | ALDH1A1HCAR2TDP1POLBAPEX1 | |
| SCHEMBL28246245 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HCAR2TDP1LMNATHRB | |
| SCHEMBL28311598 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HCAR2TDP1POLBLMNA | |
| Methacrylic Acid SCHEMBL28171879 | 0.83 | HCAR2 (0.50) | ALDH1A1HCAR2TDP1POLBLMNA | |
| Propene SCHEMBL28187730 | 0.83 | TSHR (0.52) | ALDH1A1HCAR2TDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100189890-A1 | HIGH ADHESION ACRYLATE COATINGS F0R A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (FR) | 2010-07-29 | — | — | US | claimed |
| US-7759433-B2 | High adhesion acrylate coating for a photochromic ophthalmic lens | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2010-07-20 | — | — | US | claimed |
| EP-2167306-A2 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (COMPAGNIE GENERAL D'OPTIQUE) (FR) | 2010-03-31 | — | — | EP | claimed |
| US-20090318619-A1 | INITIATORS FOR OPTICAL COATING FORMULATIONS WITH REDUCED YELLOWNESS | ESSILOR INTERNATIONAL (FR) | 2009-12-24 | — | — | US | claimed |
| US-20080315162-A1 | High adhesion acrylate coating for a photochromic ophthalmic lens | ESSILOR INTERNATIONAL (FR) | 2008-12-25 | — | — | US | claimed |
| WO-2008157607-A2 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (FR) | 2008-12-24 | — | — | WO | claimed |
| EP-2167306-B1 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INT (FR) | 2013-04-17 | — | — | EP | disclosed |
| US-8048974-B2 | Initiators for optical coating formulations with reduced yellowness | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE (FR) | 2011-11-01 | — | — | US | disclosed |
| US-20100201010-A1 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2010-08-12 | — | — | US | disclosed |
| US-20100189890-A1 | HIGH ADHESION ACRYLATE COATINGS F0R A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (FR) | 2010-07-29 | — | — | US | disclosed |
| US-7759433-B2 | High adhesion acrylate coating for a photochromic ophthalmic lens | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2010-07-20 | — | — | US | disclosed |
| EP-2167306-A2 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (COMPAGNIE GENERAL D'OPTIQUE) (FR) | 2010-03-31 | — | — | EP | disclosed |
| US-20090318619-A1 | INITIATORS FOR OPTICAL COATING FORMULATIONS WITH REDUCED YELLOWNESS | ESSILOR INTERNATIONAL (FR) | 2009-12-24 | — | — | US | disclosed |
| US-20080315162-A1 | High adhesion acrylate coating for a photochromic ophthalmic lens | ESSILOR INTERNATIONAL (FR) | 2008-12-25 | — | — | US | disclosed |
| WO-2008157607-A2 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (FR) | 2008-12-24 | — | — | WO | disclosed |