Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170802 | 0.89 | ALDH1A1 (0.53) | THRBALDH1A1HCAR2LMNACA12 | |
| SCHEMBL30152200 | 0.89 | THRB (0.56) | THRBALDH1A1HCAR2LMNACA12 | |
| SCHEMBL1395905 | 0.88 | ALDH1A1 (0.46) | THRBALDH1A1HCAR2LMNACA12 | |
| SCHEMBL628109 | 0.87 | ALDH1A1 (0.50) | THRBALDH1A1HCAR2LMNACA12 | |
| SCHEMBL2582826 | 0.86 | ALDH1A1 (0.44) | THRBALDH1A1HCAR2LMNACA12 | |
| SCHEMBL28246245 | 0.85 | ALDH1A1 (0.49) | THRBALDH1A1HCAR2LMNACA12 | |
| SCHEMBL28311598 | 0.84 | ALDH1A1 (0.47) | THRBALDH1A1HCAR2LMNACA12 | |
| Methacrylic Acid SCHEMBL28171879 | 0.84 | HCAR2 (0.50) | THRBALDH1A1HCAR2LMNACA12 | |
| SCHEMBL9638004 | 0.84 | TSHR (0.57) | THRBALDH1A1HCAR2LMNATSHR | |
| SCHEMBL28268541 | 0.84 | TSHR (0.57) | THRBALDH1A1HCAR2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020037984-A1 | High refractive index hydrogel compositions for ophthalmic implants | VANDERBILT DAVID P (US) | 2002-03-28 | — | — | US | disclosed |