Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25830260 | 1.00 | MGLL (0.43) | MGLLAGTR2FAAHSMYD3BRD4 | |
| SCHEMBL25830163 | 1.00 | MGLL (0.43) | MGLLAGTR2FAAHSMYD3BRD4 | |
| SCHEMBL25830258 | 1.00 | MGLL (0.43) | MGLLAGTR2FAAHSMYD3BRD4 | |
| SCHEMBL25487520 | 0.92 | MGLL (0.47) | MGLLAGTR2FAAHSMYD3BRD4 | |
| SCHEMBL25488081 | 0.92 | MGLL (0.47) | MGLLAGTR2FAAHSMYD3BRD4 | |
| SCHEMBL25488085 | 0.92 | MGLL (0.47) | MGLLAGTR2FAAHSMYD3BRD4 | |
| SCHEMBL25488083 | 0.92 | MGLL (0.47) | MGLLAGTR2FAAHSMYD3BRD4 | |
| SCHEMBL25830123 | 0.86 | FAAH (0.51) | MGLLFAAH | |
| SCHEMBL20566764 | 0.81 | MGLL (0.62) | MGLLAGTR2FAAH | |
| SCHEMBL20566550 | 0.81 | MGLL (0.62) | MGLLAGTR2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219897-A1 | PYRAZOLE MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219897-A1 | PYRAZOLE MAGL INHIBITORS | MGLL, PNLIP, LPL | MGLL 1/4885AGTR2 3478/4885FAAH 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.