SCHEMBL25830288

SCHEMBL25830288

CC(=O)c1ccn(C(=O)N2C[C@H]3C[C@H](NCc4cccc(-c5ccccc5)c4)C[C@H]3C2)n1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FAAH O00519 7/20 0.54
MGLL Q99685 12/20 0.49
CARM1 Q86X55 2/20 0.43
PRMT6 Q96LA8 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20920466 0.93 FAAH (0.63) FAAHMGLL
SCHEMBL30420318 0.93 FAAH (0.63) FAAHMGLL
SCHEMBL25830090 0.85 FAAH (0.58) FAAHMGLL
SCHEMBL25830298 0.83 MGLL (0.65) FAAHMGLL
SCHEMBL25830297 0.83 MGLL (0.65) FAAHMGLL
SCHEMBL25830338 0.83 MGLL (0.55) FAAHMGLL
SCHEMBL25830103 0.83 MGLL (0.55) FAAHMGLL
SCHEMBL25643351 0.79 FAAH (0.47) FAAHMGLL
SCHEMBL25830035 0.78 FAAH (0.85) FAAHMGLL
SCHEMBL25830104 0.78 FAAH (0.85) FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219897-A1 PYRAZOLE MAGL INHIBITORS H. LUNDBECK A/S (DK) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219897-A1 PYRAZOLE MAGL INHIBITORS MGLL, PNLIP, LPL FAAH 33/4885MGLL 1/4885CARM1 4493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.