SCHEMBL25830863

SCHEMBL25830863

C=CC(=O)OCc1ccc(N(c2ccccc2)c2ccc(-c3cccc(C)c3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
NR1H4 Q96RI1 3/20 0.42
HCAR2 Q8TDS4 1/20 0.42
HSD17B1 P14061 2/20 0.42
HSD17B2 P37059 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
MMP12 P39900 1/20 0.40
ENPP2 Q13822 1/20 0.39
FFAR1 O14842 1/20 0.39
MGLL Q99685 1/20 0.39
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22148976 0.92 LTB4R2 (0.39) NR1H4HSD17B1HSD17B2NPC1RAB9A
SCHEMBL12727904 0.90 MMP12 (0.43) HCAR2NPC1RAB9AMMP12ENPP2
SCHEMBL25830871 0.90 MMP12 (0.46) HCAR2NPC1RAB9AMMP12MAPT
SCHEMBL9915733 0.89 HCAR2 (0.44) HCAR2NPC1RAB9AENPP2FFAR1
SCHEMBL172202 0.88 RAB9A (0.38) HCAR2HSD17B1HSD17B2NPC1RAB9A
SCHEMBL22604963 0.88 RAB9A (0.38) HCAR2HSD17B1HSD17B2NPC1RAB9A
SCHEMBL13778858 0.88 HCAR2 (0.45) HCAR2NPC1RAB9AENPP2FFAR1
SCHEMBL12534114 0.88 HCAR2 (0.45) HCAR2NPC1RAB9AENPP2MAPT
SCHEMBL172480 0.88 HCAR2 (0.45) HCAR2NPC1RAB9AENPP2FFAR1
SCHEMBL16625916 0.88 HCAR2 (0.45) HCAR2NPC1RAB9AENPP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed