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Sugi Predict / Compounds / SCHEMBL9970457

SCHEMBL9970457

SCHEMBL9970457

C=CC(=O)OCCCOc1ccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 1/20 0.59
▸ TSHR P16473 2/20 0.45
▸ HPGD P15428 1/20 0.45
▸ HDAC1 Q13547 8/20 0.43
▸ HDAC2 Q92769 8/20 0.43
▸ HDAC3 O15379 6/20 0.43
▸ HDAC4 P56524 6/20 0.43
▸ HDAC7 Q8WUI4 6/20 0.43
▸ HDAC10 Q969S8 6/20 0.43
▸ HDAC11 Q96DB2 6/20 0.43
▸ HDAC8 Q9BY41 6/20 0.43
▸ HDAC6 Q9UBN7 6/20 0.43
▸ HDAC9 Q9UKV0 6/20 0.43
▸ HDAC5 Q9UQL6 6/20 0.43
▸ ALDH1A1 P00352 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ MMP3 P08254 1/20 0.41
▸ PPARG P37231 2/20 0.41
▸ PPARA Q07869 2/20 0.41
▸ PPARD Q03181 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23893974 0.94 THRB (0.59) THRBTSHRHPGDHDAC1HDAC2
SCHEMBL25830880 0.94 THRB (0.69) THRBTSHRHPGDHDAC1HDAC2
SCHEMBL20086240 0.91 THRB (0.69) THRBHDAC1HDAC2HDAC3HDAC4
SCHEMBL19229848 0.90 THRB (0.49) THRBTSHRHPGDPPARGPPARA
SCHEMBL25830904 0.89 THRB (0.75) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL16893759 0.89 THRB (0.69) THRBTSHRHPGDHDAC1HDAC2
SCHEMBL17528628 0.89 THRB (0.48) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL19601508 0.89 THRB (0.48) THRBTSHRHPGDALDH1A1CYP3A4
SCHEMBL25830897 0.88 THRB (0.61) THRBTSHRHPGDPPARGHTT
SCHEMBL20414483 0.88 THRB (0.47) THRBTSHRHPGDALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8203780-B2 Systems and methods for improving the performance of a photorefractive device NITTO DENKO CORPORATION (JP) 2012-06-19 — — US disclosed
US-7985356-B2 Non-linear optical device sensitive to green laser NITTO DENKO CORPORATION (JP) 2011-07-26 — — US disclosed
US-7736548-B2 Non-linear optical device with long grating persistency NITTO DENKO CORPORATION (JP) 2010-06-15 — — US disclosed
US-20100099789-A1 METHOD FOR MODULATING LIGHT OF PHOTOREFRACTIVE COMPOSITION NITTO DENKO CORPORATION (JP) 2010-04-22 — — US disclosed
US-20100096603-A1 OPTICAL DEVICES RESPONSIVE TO NEAR INFRARED LASER AND METHODS OF MODULATING LIGHT NITTO DENKO CORPORATION (JP) 2010-04-22 — — US disclosed
US-20100060975-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE NITTO DENKO CORPORATION (JP) 2010-03-11 — — US disclosed
US-20090197186-A1 OPTICAL DEVICES RESPONSIVE TO BLUE LASER AND METHOD OF MODULATING LIGHT NITTO DENKO CORPORATION (JP) 2009-08-06 — — US disclosed
US-20090092746-A1 PHOTOREFRACTIVE COMPOSITIONS WITH NANOPARTICLES NITTO DENKO CORPORATION (JP) 2009-04-09 — — US disclosed
US-20090052009-A1 NON-LINEAR OPTICAL DEVICE SENSITIVE TO GREEN LASER NITTO DENKO CORPORATION (JP) 2009-02-26 — — US disclosed
US-20080039603-A1 NON-LINEAR OPTICAL DEVICE WITH LONG GRATING PERSISTENCY NITTO DENKO CORPORATION (JP) 2008-02-14 — — US disclosed
US-7186781-B2 Fullerene-containing polymer, producing method thereof, and photorefractive composition NITTO DENKO CORPORATION (JP) 2007-03-06 — — US disclosed
US-7186781-B2 Fullerene-containing polymer, producing method thereof, and photorefractive composition NITTO DENKO CORPORATION (JP) 2007-03-06 — — US disclosed