Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12955405 | 0.85 | HTR1A (0.35) | ADRA2AADRA2BADRA2C | |
| SCHEMBL15745448 | 0.78 | ESR1 (0.42) | NPSR1ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL14650862 | 0.77 | GABRA1 (0.41) | MAPTNPSR1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL15108935 | 0.77 | KDM4E (0.47) | NPSR1L3MBTL1 | |
| SCHEMBL17029846 | 0.77 | KDM4E (0.47) | NPSR1L3MBTL1 | |
| SCHEMBL10824380 | 0.75 | GABRA1 (0.39) | MAPTNPSR1L3MBTL1ADRA2AADRA2B | |
| SCHEMBL4249036 | 0.75 | GABRA1 (0.39) | MAPTNPSR1L3MBTL1GABRA1GABRB2 | |
| SCHEMBL545484 | 0.74 | GABRA1 (0.46) | MAPTNPSR1L3MBTL1GABRA1GABRB2 | |
| SCHEMBL29657207 | 0.74 | GABRA1 (0.46) | MAPTNPSR1L3MBTL1GABRA1GABRB2 | |
| SCHEMBL6546540 | 0.74 | GABRA1 (0.42) | MAPTNPSR1L3MBTL1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125845-A1 | HETEROAROMATIC BICYCLIC COMPOUND AND ANTIVIRAL APPLICATION THEREOF | 苏州爱科百发生物医药技术有限公司 | 2023-07-06 | — | — | WO | disclosed |