Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657207 | 0.81 | GABRA1 (0.46) | GABRA1GABRB2TSHRMAPTNPSR1 | |
| SCHEMBL545484 | 0.81 | GABRA1 (0.46) | GABRA1GABRB2TSHRMAPTNPSR1 | |
| SCHEMBL6546540 | 0.81 | GABRA1 (0.42) | GABRA1GABRB2TSHRMAPTNPSR1 | |
| SCHEMBL14650862 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2TSHRMAPTNPSR1 | |
| SCHEMBL10721566 | 0.79 | GABRA1 (0.46) | GABRA1GABRB2TSHRMAPTNPSR1 | |
| SCHEMBL25066278 | 0.77 | CYP2D6 (0.42) | GABRA1GABRB2TSHRMAPTNPSR1 | |
| SCHEMBL3627333 | 0.77 | TSHR (0.59) | GABRA1GABRB2TSHRMAPTNPSR1 | |
| SCHEMBL13795689 | 0.77 | CYP2D6 (0.42) | GABRA1GABRB2TSHRMAPTNPSR1 | |
| SCHEMBL8750534 | 0.77 | GABRA1 (0.39) | GABRA1GABRB2TSHRMAPTNPSR1 | |
| SCHEMBL3931197 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2TSHRMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099192-A1 | Substituted 1H-pyrrole-2,5-diones | BAYER CROPSCIENCE AG (DE) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099192-A1 | Substituted 1H-pyrrole-2,5-diones | PYCR1, COX5A, COX5B | GABRA1 2102/4885GABRB2 2184/4885TSHR 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.