Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 11/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL3337707 | 0.99 | HDAC3 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3276632 | 0.96 | HDAC3 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Zinc Ion SCHEMBL2580314 | 0.96 | HDAC3 (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Zinc Ion SCHEMBL3337795 | 0.94 | HDAC3 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3276879 | 0.92 | HDAC3 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Zinc Ion SCHEMBL2581231 | 0.92 | HDAC3 (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3276636 | 0.86 | EPHX2 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Dihydrolipoic Acid SCHEMBL4761909 | 0.85 | NFKB1 (0.38) | — | |
| Zinc Ion SCHEMBL2575366 | 0.84 | PTPN1 (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2581324 | 0.84 | EPHX2 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048911-B2 | Melanin eliminator preparation | OGA Research, Inc. (JP) | 2011-11-01 | — | — | US | disclosed |
| US-20090093541-A1 | MELANIN ELIMINATOR PREPARATION | OGA RESEARCH, INC (JP) | 2009-04-09 | — | — | US | disclosed |
| US-20060122100-A1 | Melanin extinguisher | OGA RESEARCH, INCORPORATED (JP) | 2006-06-08 | — | — | US | disclosed |
| EP-1547590-A1 | MELANIN EXTINGUISHER | Oga Research, Incorporated (JP) | 2005-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122100-A1 | Melanin extinguisher | TYR, MC1R, MITF | HDAC3 2885/4885HDAC4 3186/4885HDAC1 1609/4885 |
| US-20090093541-A1 | MELANIN ELIMINATOR PREPARATION | TYR, MC1R, MCHR1 | HDAC3 3339/4885HDAC4 3112/4885HDAC1 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.