Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 11/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zinc Ion SCHEMBL2583379 | 0.99 | HDAC3 (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3276632 | 0.97 | HDAC3 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Zinc Ion SCHEMBL3337795 | 0.96 | HDAC3 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Zinc Ion SCHEMBL2580314 | 0.94 | HDAC3 (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3276879 | 0.93 | HDAC3 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Zinc Ion SCHEMBL2581231 | 0.90 | HDAC3 (0.35) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2581324 | 0.85 | EPHX2 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16312532 | 0.85 | PTPN1 (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Dihydrolipoic Acid SCHEMBL2582100 | 0.84 | NFKB1 (0.39) | — | |
| SCHEMBL3337710 | 0.84 | EPHX2 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152288-A1 | NOVEL a-LIPOIC ACID DERIVATIVES AND APPLICATIONS THEREOF | SENJU PHARMACEUTICAL CO. LTD. (JP) | 2010-06-17 | — | — | US | claimed |
| EP-1371640-B1 | NOVEL A-LIPOIC ACID DERIVATIVE AND USE THEREOF | SENJU PHARMA CO (JP) | 2009-10-28 | — | — | EP | claimed |
| EP-1371640-B1 | NOVEL A-LIPOIC ACID DERIVATIVE AND USE THEREOF | SENJU PHARMA CO (JP) | 2009-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152288-A1 | NOVEL a-LIPOIC ACID DERIVATIVES AND APPLICATIONS THEREOF | TYR, SERPINB1, LPO | HDAC3 4462/4885HDAC4 3832/4885HDAC1 1959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.