Zinc Ion

Zinc Ion

SCHEMBL2575366

O=C([O-])CNC(=O)CCCCC(S)CCS.O=C([O-])CNC(=O)CCCCC(S)CCS.[NaH].[Zn+2]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.37
FAAH O00519 2/20 0.36
RECQL P46063 1/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
GAA P10253 1/20 0.32
HDAC3 O15379 4/20 0.31
HDAC4 P56524 4/20 0.31
HDAC1 Q13547 4/20 0.31
HDAC7 Q8WUI4 4/20 0.31
HDAC2 Q92769 4/20 0.31
HDAC10 Q969S8 4/20 0.31
HDAC11 Q96DB2 4/20 0.31
HDAC8 Q9BY41 4/20 0.31
HDAC6 Q9UBN7 4/20 0.31
HDAC9 Q9UKV0 4/20 0.31
HDAC5 Q9UQL6 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL3335093 0.98 PTPN1 (0.38) PTPN1FAAHRECQLCA12CA1
SCHEMBL3283758 0.95 PTPN1 (0.38) PTPN1FAAHRECQLCA12CA1
Zinc Ion SCHEMBL2581231 0.87 HDAC3 (0.35) PTPN1FAAHHDAC3HDAC4HDAC1
Zinc Ion SCHEMBL2580314 0.85 HDAC3 (0.35) FAAHHDAC3HDAC4HDAC1HDAC7
SCHEMBL3283754 0.84 PTPN1 (0.53) PTPN1FAAHRECQLHDAC3HDAC4
Zinc Ion SCHEMBL2583379 0.84 HDAC3 (0.40) FAAHHDAC3HDAC4HDAC1HDAC7
Zinc Ion SCHEMBL3337795 0.84 HDAC3 (0.36) FAAHHDAC3HDAC4HDAC1HDAC7
SCHEMBL2580508 0.83 PTPN1 (0.54) PTPN1FAAHRECQLHDAC3HDAC4
Zinc Ion SCHEMBL3337707 0.82 HDAC3 (0.41) FAAHHDAC3HDAC4HDAC1HDAC7
Dihydrolipoic Acid SCHEMBL4761909 0.82 NFKB1 (0.38) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION OGA RESEARCH, INC (JP) 2009-04-09 US disclosed
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US disclosed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122100-A1 Melanin extinguisher TYR, MC1R, MITF PTPN1 103/4885FAAH 4202/4885RECQL 3995/4885
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION TYR, MC1R, MCHR1 PTPN1 499/4885FAAH 3678/4885RECQL 3510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.