Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2580508 | 0.98 | PTPN1 (0.54) | PTPN1FAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL3335091 | 0.97 | PTPN1 (0.53) | PTPN1FAAHMEN1KMT2AALDH1A1 | |
| Zinc Ion SCHEMBL2575366 | 0.84 | PTPN1 (0.37) | PTPN1FAAHRECQLHDAC3HDAC4 | |
| SCHEMBL2575373 | 0.84 | FAAH (0.42) | PTPN1FAAHGSTK1ENPEPHDAC3 | |
| SCHEMBL3276636 | 0.83 | EPHX2 (0.47) | PTPN1KDM4ELMNAGSTK1HDAC3 | |
| Zinc Ion SCHEMBL3335093 | 0.83 | PTPN1 (0.38) | PTPN1FAAHRECQLHDAC3HDAC4 | |
| SCHEMBL3283758 | 0.83 | PTPN1 (0.38) | PTPN1FAAHRECQLHDAC3HDAC4 | |
| SCHEMBL2582831 | 0.83 | KDM4E (0.43) | MEN1KMT2AMAPTKDM4ESLC6A5 | |
| SCHEMBL2576305 | 0.81 | PTGS1 (0.46) | PTPN1FAAHALDH1A1MAPTTDP1 | |
| SCHEMBL2581324 | 0.81 | EPHX2 (0.48) | KDM4ELMNAGSTK1ENPEPHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10632089-B2 | Tyrosinase activity inhibitor and external preparation for skin | JO COSMETICS CO., LTD. (JP) | 2020-04-28 | — | — | US | disclosed |
| US-20180071239-A1 | TYROSINASE ACTIVITY INHIBITOR AND EXTERNAL PREPARATION FOR SKIN | JO COSMETICS CO., LTD. (JP) | 2018-03-15 | — | — | US | disclosed |
| US-20100152288-A1 | NOVEL a-LIPOIC ACID DERIVATIVES AND APPLICATIONS THEREOF | SENJU PHARMACEUTICAL CO. LTD. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-7700080-B2 | Method of suppressing melanin production by metal chelates of lipoyl amino acid derivatives | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| EP-1371640-B1 | NOVEL A-LIPOIC ACID DERIVATIVE AND USE THEREOF | SENJU PHARMA CO (JP) | 2009-10-28 | — | — | EP | disclosed |
| US-20040092586-A1 | Novel a-lipoic acid derivative and use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1371640-A1 | NOVEL A-LIPOIC ACID DERIVATIVE AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 2003-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10632089-B2 | Tyrosinase activity inhibitor and external preparation for skin | TYR, SOD1, CAT | PTPN1 1905/4885FAAH 3929/4885MEN1 2442/4885 |
| US-20100152288-A1 | NOVEL a-LIPOIC ACID DERIVATIVES AND APPLICATIONS THEREOF | TYR, SERPINB1, LPO | PTPN1 1112/4885FAAH 1636/4885MEN1 1715/4885 |
| US-20180071239-A1 | TYROSINASE ACTIVITY INHIBITOR AND EXTERNAL PREPARATION FOR SKIN | TYR, SOD1, CAT | PTPN1 1905/4885FAAH 3929/4885MEN1 2442/4885 |
| US-20040092586-A1 | Novel a-lipoic acid derivative and use thereof | TYR, SERPINB1, LPO | PTPN1 1346/4885FAAH 1603/4885MEN1 1581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.