Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25C | P30307 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.44 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.44 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27759840 | 0.84 | MAPT (0.50) | TOP1MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL16072720 | 0.81 | KCNA3 (0.58) | MAPTMAPK1TDP1L3MBTL1MAOB | |
| SCHEMBL9173435 | 0.80 | KCNA3 (0.56) | MAPTMAPK1TDP1L3MBTL1MAOB | |
| SCHEMBL9754264 | 0.79 | KCNA3 (0.63) | MAPTMAPK1TDP1L3MBTL1MAOB | |
| SCHEMBL8216313 | 0.78 | MAPT (0.69) | MAPTMAPK1TDP1L3MBTL1MAOB | |
| SCHEMBL24194098 | 0.78 | TOP1 (0.66) | TOP1MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL30574283 | 0.78 | TOP1 (0.66) | TOP1MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL30660808 | 0.77 | MAPT (0.50) | MAPTMAPK1TDP1L3MBTL1MAOB | |
| SCHEMBL5838519 | 0.77 | MAPT (0.50) | MAPTMAPK1TDP1L3MBTL1MAOB | |
| SCHEMBL8599835 | 0.76 | MAOA (0.54) | MAPTMAPK1TDP1L3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113368087-A | Juglone derivatives and application thereof in preparation of drugs for treating brain tumors through chemotherapy | 复旦大学附属华山医院 | 2021-09-10 | — | — | CN | claimed |
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | THE UNIVERSITY OF HONG KONG (CN) | 2023-07-20 | — | — | US | disclosed |
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | THE UNIVERSITY OF HONG KONG (CN) | 2023-07-20 | — | — | US | disclosed |
| CN-113368087-A | Juglone derivatives and application thereof in preparation of drugs for treating brain tumors through chemotherapy | 复旦大学附属华山医院 | 2021-09-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227393-A1 | IRON CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES | NFE2L2, DUOX1, DUOX2 | TOP1 1011/4885MAPT 736/4885MAPK1 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.