Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25835103 | 0.77 | HPGD (0.46) | ADRA1AGABRA5VNN1HPGDGRM5 | |
| SCHEMBL25834984 | 0.72 | VNN1 (0.46) | ADRA1AGABRA5HCAR3VNN1FASN | |
| SCHEMBL25834424 | 0.71 | HCAR3 (0.57) | ADRA1AHCAR3VNN1GRM5 | |
| SCHEMBL25834560 | 0.71 | VNN1 (0.48) | ADRA1AGABRA5VNN1HPGDGRM5 | |
| SCHEMBL15205661 | 0.69 | ATM (0.43) | HCAR3HPGD | |
| SCHEMBL25342374 | 0.69 | VNN1 (0.50) | ADRA1AGABRA5VNN1HPGDGRM5 | |
| SCHEMBL30589658 | 0.69 | VNN1 (0.50) | ADRA1AGABRA5VNN1HPGDGRM5 | |
| SCHEMBL18291340 | 0.69 | PIK3CA (0.47) | — | |
| SCHEMBL25835199 | 0.69 | VNN1 (0.56) | ADRA1AVNN1HPGDGRM5 | |
| SCHEMBL25834884 | 0.69 | HCAR3 (0.58) | ADRA1AHCAR3VNN1HPGDGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137356-A1 | 15-PGDH INHIBITORS | VENTYX BIOSCIENCES, INC. (US) | 2023-07-20 | — | — | WO | disclosed |