Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 7/20 | 0.56 |
| ▸ | GRM5 | P41594 | 10/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25834424 | 0.81 | HCAR3 (0.57) | VNN1GRM5ADRA1A | |
| SCHEMBL25834560 | 0.81 | VNN1 (0.48) | VNN1GRM5ADRA1AHPGDKDM4E | |
| SCHEMBL25834984 | 0.79 | VNN1 (0.46) | VNN1GRM5ADRA1AKDM4EALDH1A1 | |
| SCHEMBL25834884 | 0.78 | HCAR3 (0.58) | VNN1GRM5ADRA1AHPGDKDM4E | |
| SCHEMBL25342374 | 0.76 | VNN1 (0.50) | VNN1GRM5ADRA1AHPGDALDH1A1 | |
| SCHEMBL30589658 | 0.76 | VNN1 (0.50) | VNN1GRM5ADRA1AHPGDALDH1A1 | |
| SCHEMBL25835103 | 0.76 | HPGD (0.46) | VNN1GRM5ADRA1AHPGDKDM4E | |
| SCHEMBL16345854 | 0.75 | VNN1 (0.49) | VNN1GRM5ADRA1AHPGDALDH1A1 | |
| SCHEMBL25834104 | 0.75 | RAB9A (0.58) | VNN1GRM5ADRA1AHPGD | |
| SCHEMBL25296254 | 0.72 | GRM5 (0.58) | GRM5HPGDKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137356-A1 | 15-PGDH INHIBITORS | VENTYX BIOSCIENCES, INC. (US) | 2023-07-20 | — | — | WO | disclosed |