Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 5/20 | 0.47 |
| ▸ | PARP1 | P09874 | 11/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24341742 | 0.89 | RAB9A (0.48) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL23455432 | 0.89 | RAB9A (0.50) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL23455430 | 0.89 | RAB9A (0.50) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL20057655 | 0.88 | CYP17A1 (0.39) | PARP14HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL19275814 | 0.86 | ALDH1A1 (0.47) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL17569733 | 0.86 | ALDH1A1 (0.47) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30725576 | 0.85 | SMN1; SMN2 (0.43) | KMT2AALDH1A1CYP17A1 | |
| SCHEMBL16355923 | 0.83 | MEN1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3785111 | 0.82 | CTSK (0.41) | MEN1KMT2AHDAC1ALDH1A1CYP17A1 | |
| SCHEMBL13785635 | 0.82 | CTSK (0.41) | MEN1KMT2AHDAC1ALDH1A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226193-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. | 2023-07-20 | — | — | US | disclosed |
| US-20230226193-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226193-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | CPT1B, MUSK, MYLK2 | PARP14 2807/4885PARP1 1719/4885PARP10 3166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.