Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21137981 | 1.00 | PYGB (0.38) | PYGBPTGS2PTGS1CXCR1CXCR2 | |
| SCHEMBL23104795 | 0.92 | MAPK1 (0.40) | PYGBPTGS2PTGS1CXCR1CXCR2 | |
| SCHEMBL21058392 | 0.92 | MAPK1 (0.40) | PYGBPTGS2PTGS1CXCR1CXCR2 | |
| SCHEMBL25835021 | 0.92 | MAPK1 (0.40) | PYGBPTGS2PTGS1CXCR1CXCR2 | |
| SCHEMBL25839524 | 0.90 | PYGB (0.42) | PYGBPTGS2PTGS1CXCR1CXCR2 | |
| SCHEMBL21058345 | 0.85 | SSTR3 (0.45) | — | |
| SCHEMBL21138772 | 0.84 | PTGS2 (0.42) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL25959074 | 0.82 | PTGS2 (0.39) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL25957583 | 0.79 | PTGS2 (0.37) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL25835418 | 0.78 | PYGB (0.44) | PYGBALDH1A1SMN1; SMN2SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227488-A1 | GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | RISEN SUZHOU PHARMA TECH CO LTD (CN) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227488-A1 | GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | OGT, UGGT1, GLA | PYGB 601/4885PTGS2 702/4885PTGS1 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.