SCHEMBL21058392

SCHEMBL21058392

CCCC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1OC(=O)C(C)c1ccc(CC(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.40
▸ PYGB P11216 1/20 0.39
▸ PTGS2 P35354 6/20 0.38
▸ PTGS1 P23219 3/20 0.38
▸ CXCR1 P25024 3/20 0.38
▸ CXCR2 P25025 3/20 0.38
▸ LMNA P02545 2/20 0.38
▸ CYP2C9 P11712 2/20 0.38
▸ AKR1C3 P42330 2/20 0.38
▸ ALB P02768 1/20 0.38
▸ ESR1 P03372 1/20 0.38
▸ ALOX5 P09917 1/20 0.38
▸ RARB P10826 1/20 0.38
▸ ADRB3 P13945 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ HTR2A P28223 1/20 0.38
▸ NR1I3 Q14994 1/20 0.38
▸ SLC22A6 Q4U2R8 1/20 0.38
▸ CXCL8 P10145 1/20 0.38
▸ TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23104795 1.00 MAPK1 (0.40) MAPK1PYGBPTGS2PTGS1CXCR1
SCHEMBL25835021 1.00 MAPK1 (0.40) MAPK1PYGBPTGS2PTGS1CXCR1
SCHEMBL21137981 0.92 PYGB (0.38) PYGBPTGS2PTGS1CXCR1CXCR2
SCHEMBL25835269 0.92 PYGB (0.38) PYGBPTGS2PTGS1CXCR1CXCR2
SCHEMBL25839524 0.91 PYGB (0.42) PYGBPTGS2PTGS1CXCR1CXCR2
SCHEMBL21058345 0.86 SSTR3 (0.45) —
SCHEMBL25957583 0.85 PTGS2 (0.37) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL21058347 0.84 PTGS2 (0.43) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL25959074 0.83 PTGS2 (0.39) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL21138772 0.78 PTGS2 (0.42) PTGS2PTGS1CXCR1CXCR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2026-02-17 — — US disclosed
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2025-11-20 — — US disclosed
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2025-05-27 — — US disclosed
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2024-02-15 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
CN-115594724-A Glucosamine derivatives for preventing or treating joint diseases 润佳(苏州)医药科技有限公司(CN) 2023-01-13 — — CN disclosed
CN-115215911-A Glucosamine derivative, composition thereof and medical application thereof 润佳(苏州)医药科技有限公司 2022-10-21 — — CN disclosed
CN-111971290-B Glucosamine derivatives for preventing or treating joint diseases 润佳(苏州)医药科技有限公司 2022-10-14 — — CN disclosed
CN-109929001-B Glucosamine derivative, composition thereof and medical application thereof 润佳(苏州)医药科技有限公司 2022-07-08 — — CN disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
CN-111971290-A Glucosamine derivatives for preventing or treating joint diseases 润佳(苏州)医药科技有限公司 2020-11-20 — — CN disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353870-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA MAPK1 846/4885PYGB 601/4885PTGS2 702/4885
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA MAPK1 887/4885PYGB 760/4885PTGS2 648/4885
US-20240051982-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, FUT6 MAPK1 599/4885PYGB 802/4885PTGS2 443/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA MAPK1 887/4885PYGB 760/4885PTGS2 648/4885
US-12552823-B2 Glucosamine derivatives and pharmaceutical uses thereof SOST, FUT6, SLC5A1 MAPK1 294/4885PYGB 675/4885PTGS2 1046/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA MAPK1 846/4885PYGB 601/4885PTGS2 702/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA MAPK1 846/4885PYGB 601/4885PTGS2 702/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA MAPK1 846/4885PYGB 601/4885PTGS2 702/4885
US-12312378-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, FUT6 MAPK1 599/4885PYGB 802/4885PTGS2 443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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