Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | DNM2 | P50570 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10630922 | 0.64 | ADRA2A (0.36) | ALPLALPITLR8PTGS2 | |
| SCHEMBL514975 | 0.60 | KCNH3 (0.63) | KCNH3DNM2KMT2A | |
| SCHEMBL2574753 | 0.60 | KCNH3 (0.59) | KCNH3DNM2KMT2A | |
| SCHEMBL3298621 | 0.59 | KMT2A (0.67) | KCNH3DNM2KMT2A | |
| SCHEMBL3299537 | 0.59 | KMT2A (0.67) | KCNH3DNM2KMT2A | |
| SCHEMBL403583 | 0.59 | KMT2A (0.67) | KCNH3DNM2KMT2A | |
| SCHEMBL14441528 | 0.59 | KMT2A (0.67) | KCNH3DNM2KMT2A | |
| SCHEMBL8054465 | 0.59 | KMT2A (0.67) | KCNH3DNM2KMT2A | |
| SCHEMBL14441519 | 0.59 | KMT2A (0.67) | KCNH3DNM2KMT2A | |
| SCHEMBL1032562 | 0.59 | KMT2A (0.67) | KCNH3DNM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135057-A1 | BICYCLIC TRIAZINE DERIVATIVES FOR THE TREATMENT OF CANCER | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2023-07-20 | — | — | WO | disclosed |