SCHEMBL25835493

SCHEMBL25835493

CCCC/C=C\CCCC(=O)NCCOCCNC(=O)CC[C@H](NC(=O)OC(C)(C)C)C(=O)NCCOCCNC(=O)CCC/C=C\CCCC

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 1/20 0.50
GLP1R P43220 8/20 0.48
CTSS P25774 2/20 0.48
CTSK P43235 2/20 0.48
CNR1 P21554 4/20 0.45
ENPP2 Q13822 1/20 0.41
LPAR1 Q92633 1/20 0.41
LPAR2 Q9HBW0 1/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032874 0.93 GLP1R (0.55) CAPN1GLP1RCTSSCTSKCNR1
SCHEMBL26032556 0.90 GLP1R (0.50) GLP1RCNR1
SCHEMBL25835683 0.89 GLP1R (0.59) CAPN1GLP1RCTSSCTSKLPAR1
SCHEMBL26032865 0.89 GLP1R (0.61) CAPN1GLP1RCTSSCTSKBCHE
SCHEMBL25835480 0.87 CTSK (0.52) CAPN1GLP1RCTSSCTSKBCHE
SCHEMBL25835366 0.86 GLP1R (0.55) CAPN1GLP1RCTSSCTSKLPAR1
SCHEMBL26032519 0.86 GLP1R (0.55) CAPN1GLP1RCTSSCTSKLPAR1
SCHEMBL26032522 0.85 CTSK (0.50) CAPN1GLP1RCTSSCTSKBCHE
SCHEMBL16853275 0.82 GLP1R (0.58) CAPN1GLP1RCTSSCTSKLPAR1
SCHEMBL20341078 0.82 GLP1R (0.58) CAPN1GLP1RCTSSCTSKLPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 CAPN1 3157/4885GLP1R 1985/4885CTSS 3695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.