Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22226364 | 0.77 | KDM4E (0.51) | GPR139SMN1; SMN2 | |
| SCHEMBL29431437 | 0.75 | GPR139 (0.44) | GPR139 | |
| SCHEMBL22162904 | 0.75 | SMN1; SMN2 (0.34) | GPR139SMN1; SMN2 | |
| SCHEMBL22006727 | 0.75 | CASP3 (0.33) | GPR139 | |
| SCHEMBL22162915 | 0.75 | AHR (0.37) | GPR139SMN1; SMN2 | |
| SCHEMBL25512531 | 0.72 | GPR139 (0.37) | GPR139SMN1; SMN2 | |
| SCHEMBL25835485 | 0.71 | CYP1A2 (0.48) | GPR139ADORA3ADORA1 | |
| SCHEMBL23414771 | 0.70 | KDM4E (0.66) | ADORA3ADORA1SMN1; SMN2 | |
| SCHEMBL23414745 | 0.70 | METTL3 (0.46) | ADORA3ADORA1SMN1; SMN2 | |
| SCHEMBL23414957 | 0.69 | METTL3 (0.47) | ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137356-A1 | 15-PGDH INHIBITORS | VENTYX BIOSCIENCES, INC. (US) | 2023-07-20 | — | — | WO | disclosed |