SCHEMBL25835682

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25835553	0.88	GRM2 (0.44)	ALOX5APFEN1GRM2AAK1NPC1
	SCHEMBL25835684	0.83	IDO1 (0.41)	ALPLAAK1MAPTTGFBR1ACVR1B
	SCHEMBL25835681	0.80	GRM2 (0.45)	GRM2L3MBTL1
	SCHEMBL26192317	0.76	L3MBTL1 (0.40)	GRM2MAPTL3MBTL1
	SCHEMBL26193310	0.75	GRM2 (0.42)	ALOX5APFEN1GRM2AAK1L3MBTL1
	SCHEMBL5857430	0.74	KCNA5 (0.52)	L3MBTL1
	SCHEMBL25836843	0.74	GRM2 (0.43)	ALOX5APFEN1GRM2AAK1NPC1
	SCHEMBL30510038	0.74	GRM2 (0.43)	ALOX5APFEN1GRM2AAK1NPC1
	SCHEMBL12791296	0.74	P2RX7 (0.46)	GRM2P2RX7
	SCHEMBL30509985	0.72	NTRK1 (0.46)	ALOX5APFEN1GRM2AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.