Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.49 |
| ▸ | DHFR | P00374 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | GALR1 | P47211 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25836130 | 0.84 | DHODH (0.49) | DHODHDHFRXDHGALR1DYRK1A | |
| SCHEMBL24180475 | 0.84 | DHODH (0.49) | DHODHDHFRXDHGALR1DYRK1A | |
| SCHEMBL29441254 | 0.83 | DHODH (0.50) | DHODHDHFRXDHGALR1DYRK1A | |
| SCHEMBL21363278 | 0.76 | XDH (0.44) | DHODHXDHGALR1DYRK1AKCNH2 | |
| SCHEMBL29019396 | 0.74 | DHODH (0.44) | DHODHDHFRXDHGALR1 | |
| SCHEMBL5840598 | 0.73 | SLC13A5 (0.51) | DHODHXDHGALR1DYRK1AKCNH2 | |
| SCHEMBL3560562 | 0.73 | DHODH (0.40) | DHODHDHFRXDHGALR1DYRK1A | |
| SCHEMBL3147185 | 0.72 | GPR3 (0.50) | XDHGALR1 | |
| SCHEMBL24315321 | 0.72 | ADORA1 (0.41) | DHODHXDHGALR1DYRK1AKCNH2 | |
| SCHEMBL159683 | 0.71 | GPR3 (0.42) | XDHGALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118576-A1 | DHODH INHIBITORS CONTAINING A CARBOXYLIC ACID BIOISOSTERE | IMMUNIC AG (DE) | 2023-06-29 | — | — | WO | disclosed |