Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 11/20 | 0.44 |
| ▸ | DHFR | P00374 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29441254 | 0.83 | DHODH (0.50) | DHODHDHFRXDHGALR1 | |
| SCHEMBL20550965 | 0.75 | FFAR1 (0.43) | DHODHTHRATHRBP2RX1TRPV3 | |
| SCHEMBL25836138 | 0.74 | DHODH (0.49) | DHODHDHFRXDHGALR1 | |
| SCHEMBL25836130 | 0.74 | DHODH (0.49) | DHODHDHFRXDHGALR1 | |
| SCHEMBL24180475 | 0.74 | DHODH (0.49) | DHODHDHFRXDHGALR1 | |
| SCHEMBL30045573 | 0.73 | THRA (0.45) | DHODHTHRATHRBP2RX1TRPV3 | |
| SCHEMBL3560562 | 0.73 | DHODH (0.40) | DHODHDHFRTRPV3XDHGALR1 | |
| SCHEMBL1031161 | 0.73 | HSD17B1 (0.52) | DHODHXDHGALR1 | |
| SCHEMBL5379608 | 0.71 | ESR1 (0.55) | DHODHXDHGALR1 | |
| SCHEMBL29320206 | 0.71 | AURKA (0.49) | DHODHXDHGALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003123-B | Modulators of the PGI2 receptor for the treatment of prostacyclin (PGI 2) receptor related disorders | 艾尼纳制药公司 | 2023-06-23 | — | — | CN | disclosed |