Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 10/20 | 0.50 |
| ▸ | DHFR | P00374 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | GALR1 | P47211 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180475 | 0.83 | DHODH (0.49) | DHODHDHFRXDHGALR1DYRK1A | |
| SCHEMBL25836138 | 0.83 | DHODH (0.49) | DHODHDHFRXDHGALR1DYRK1A | |
| SCHEMBL25836130 | 0.83 | DHODH (0.49) | DHODHDHFRXDHGALR1DYRK1A | |
| SCHEMBL29019396 | 0.83 | DHODH (0.44) | DHODHDHFRXDHGALR1 | |
| SCHEMBL3560562 | 0.79 | DHODH (0.40) | DHODHDHFRXDHGALR1DYRK1A | |
| SCHEMBL31711762 | 0.77 | HSD17B1 (0.33) | — | |
| SCHEMBL24315292 | 0.76 | ADORA1 (0.48) | DHODHXDHGALR1DYRK1AKCNH2 | |
| SCHEMBL5840598 | 0.76 | SLC13A5 (0.51) | DHODHXDHGALR1DYRK1AKCNH2 | |
| SCHEMBL1337684 | 0.75 | DHODH (0.48) | DHODHXDHGALR1DYRK1AKCNH2 | |
| SCHEMBL3147185 | 0.74 | GPR3 (0.50) | XDHGALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370111-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023285371-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT HAMBURG (DE) | 2023-01-19 | — | — | WO | disclosed |
| EP-4119138-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2023-01-18 | — | — | EP | disclosed |
| US-20220227720-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | AIX-MARSEILLE UNIVERSITE (FR) | 2022-07-21 | — | — | US | disclosed |
| EP-3965753-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2022-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227720-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | DHODH, DHX15, DHX29 | DHODH 1/4885DHFR 45/4885XDH 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.