SCHEMBL25837284

SCHEMBL25837284

CN(C)C(=O)c1ccc2c(c1)C(C)(C)C(/C=C/C1=C(N(c3ccccc3)c3ccccc3)/C(=C/C=C3/N(C)c4ccc(C(=O)N(C)C)cc4C3(C)C)CC1)=[N+]2C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 11/20 0.39
LMNA P02545 10/20 0.39
MAPT P10636 10/20 0.39
KMT2A Q03164 8/20 0.39
SMN1; SMN2 Q16637 7/20 0.39
MEN1 O00255 7/20 0.39
KDM4E B2RXH2 6/20 0.39
ALDH1A1 P00352 5/20 0.39
NPC1 O15118 4/20 0.39
POLB P06746 4/20 0.39
THRB P10828 4/20 0.39
RAB9A P51151 4/20 0.39
TDP1 Q9NUW8 4/20 0.39
PKM P14618 3/20 0.39
XBP1 P17861 3/20 0.39
S1PR4 O95977 2/20 0.39
ALPG P10696 2/20 0.39
S1PR1 P21453 2/20 0.39
NTSR1 P30989 2/20 0.39
ALOX12 P18054 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13476159 0.93 HTT (0.38) HTTLMNAMAPTKMT2ASMN1; SMN2
SCHEMBL14363977 0.93 HTT (0.38) HTTLMNAMAPTKMT2ASMN1; SMN2
SCHEMBL25862060 0.93 HTT (0.38) HTTLMNAMAPTKMT2ASMN1; SMN2
SCHEMBL25837290 0.92 LMNA (0.37) HTTLMNAMAPTKMT2ASMN1; SMN2
SCHEMBL14363973 0.91 MAPT (0.49) HTTLMNAMAPTKMT2ASMN1; SMN2
SCHEMBL25837292 0.91 MAPT (0.38) HTTLMNAMAPTKMT2ASMN1; SMN2
SCHEMBL26682569 0.90 LMNA (0.36) HTTLMNAMAPTKMT2ASMN1; SMN2
SCHEMBL14363983 0.89 MAPT (0.41) HTTLMNAMAPTKMT2ASMN1; SMN2
SCHEMBL25837273 0.89 VDR (0.41) HTTLMNAMAPTKMT2ASMN1; SMN2
SCHEMBL25837294 0.89 MAPT (0.37) HTTLMNAMAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226814-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-20230219336-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-13 US disclosed
US-20230127702-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed