SCHEMBL25837290

SCHEMBL25837290

CN1/C(=C/C=C2\CCC(/C=C/C3=[N+](C)c4ccc(C(N)=O)cc4C3(C)C)=C2N(c2ccccc2)c2ccccc2)C(C)(C)c2cc(C(N)=O)ccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 10/20 0.37
MAPT P10636 8/20 0.37
HTT P42858 8/20 0.37
MEN1 O00255 7/20 0.37
KMT2A Q03164 7/20 0.37
SMN1; SMN2 Q16637 7/20 0.37
RAB9A P51151 5/20 0.37
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 5/20 0.37
NPC1 O15118 4/20 0.37
POLB P06746 4/20 0.37
THRB P10828 4/20 0.37
PKM P14618 3/20 0.37
XBP1 P17861 3/20 0.37
S1PR4 O95977 2/20 0.37
ALPG P10696 2/20 0.37
S1PR1 P21453 2/20 0.37
NTSR1 P30989 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALOX12 P18054 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13476159 0.94 HTT (0.38) LMNAMAPTHTTMEN1KMT2A
SCHEMBL14363977 0.94 HTT (0.38) LMNAMAPTHTTMEN1KMT2A
SCHEMBL25862060 0.93 HTT (0.38) LMNAMAPTHTTMEN1KMT2A
SCHEMBL25837284 0.92 HTT (0.39) LMNAMAPTHTTMEN1KMT2A
SCHEMBL14363973 0.91 MAPT (0.49) LMNAMAPTHTTMEN1KMT2A
SCHEMBL25837292 0.91 MAPT (0.38) LMNAMAPTHTTMEN1KMT2A
SCHEMBL26682569 0.91 LMNA (0.36) LMNAMAPTHTTMEN1KMT2A
SCHEMBL14363983 0.90 MAPT (0.41) LMNAMAPTHTTMEN1KMT2A
SCHEMBL25837294 0.90 MAPT (0.37) LMNAMAPTHTTMEN1KMT2A
SCHEMBL25837273 0.90 VDR (0.41) LMNAMAPTHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226814-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-20230219336-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-13 US disclosed
US-20230127702-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-04-27 US disclosed