Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13230477 | 0.79 | ADRB2 (0.44) | ADRB2SMARCA2IDH1IDH2AR | |
| SCHEMBL20889919 | 0.79 | GRIN2D (0.36) | CHRNA7SMARCA2 | |
| SCHEMBL25825818 | 0.78 | HTR7 (0.35) | CHRNA7SMARCA2 | |
| SCHEMBL12356608 | 0.77 | TDP1 (0.40) | CHRNA7SMARCA2IDH2 | |
| SCHEMBL14184999 | 0.75 | UHRF1 (0.46) | SMARCA2 | |
| SCHEMBL17465712 | 0.73 | LOXL2 (0.38) | IDH1IDH2AR | |
| SCHEMBL8322982 | 0.73 | SMARCA2 (0.47) | SMARCA2AR | |
| SCHEMBL12695028 | 0.72 | CHRNA7 (0.31) | CHRNA7 | |
| SCHEMBL14185014 | 0.72 | PRKCI (0.47) | IDH1IDH2AR | |
| SCHEMBL23015822 | 0.71 | TYK2 (0.47) | SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | ADRB2 3606/4885CHRNA7 4724/4885SMARCA2 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.