Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RRM2 | P31350 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20889919 | 0.79 | GRIN2D (0.36) | CHRNA7SMARCA2ADRA1DADRA1AADRA1B | |
| SCHEMBL17613365 | 0.78 | ADRA2A (0.30) | ADRA2AADRA2BADRA2C | |
| SCHEMBL25837676 | 0.78 | ADRB2 (0.35) | CHRNA7SMARCA2 | |
| SCHEMBL12356608 | 0.77 | TDP1 (0.40) | HTR7CHRNA7SMARCA2MAPT | |
| SCHEMBL19223206 | 0.75 | UHRF1 (0.46) | ADRA2AADRA2BADRA2CSMARCA2 | |
| SCHEMBL11090712 | 0.75 | EGFR (0.41) | HTR7MAPTEGFR | |
| SCHEMBL23624134 | 0.73 | PRKCI (0.48) | ADRA2AADRA2BADRA2CMAPTEGFR | |
| SCHEMBL15860423 | 0.73 | LOXL2 (0.42) | HTR7ADRA2AADRA2BADRA2C | |
| SCHEMBL1098190 | 0.73 | NOS2 (0.52) | ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL4635970 | 0.73 | SMARCA2 (0.47) | SMARCA2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | HTR7 2614/4885ELANE 2543/4885RAF1 126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.