Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL28547565 | 0.98 | KCNN4 (0.40) | KCNN4KIF11TAAR1SIGMAR1LMNA | |
| SCHEMBL21577161 | 0.83 | SIGMAR1 (0.40) | KIF11SIGMAR1MAPK1SMN1; SMN2MEN1 | |
| SCHEMBL20752447 | 0.82 | TAAR1 (0.40) | KCNN4KIF11TAAR1SIGMAR1LMNA | |
| SCHEMBL950778 | 0.80 | KIF11 (0.54) | KCNN4KIF11TAAR1SIGMAR1CYP3A4 | |
| SCHEMBL2583837 | 0.80 | KCNN4 (0.44) | KCNN4KIF11TAAR1CYP2C19MAPK1 | |
| SCHEMBL6682083 | 0.78 | KCNN4 (0.43) | KCNN4KIF11TAAR1SIGMAR1LMNA | |
| Bromide SCHEMBL29549720 | 0.78 | KIF11 (0.52) | KCNN4KIF11SIGMAR1CYP3A4CYP2D6 | |
| Iodide SCHEMBL28747539 | 0.78 | KIF11 (0.52) | KCNN4KIF11SIGMAR1CYP3A4CYP2D6 | |
| SCHEMBL6700733 | 0.77 | ESR1 (0.38) | KCNN4LMNARAB9AESR1ESR2 | |
| SCHEMBL7918679 | 0.77 | CYP19A1 (0.43) | KIF11LMNAMAPK1TSHRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313580-A | Chemically amplified positive resist composition for pattern profile improvement | 荣昌化学制品株式会社 | 2021-02-02 | — | — | CN | disclosed |
| EP-0929534-A1 | TRYCYCLIC COMPOUNDS AS PROSTAGLANDIN I2 RECEPTOR AGONISTS | Takeda Pharmaceutical Company Limited (JP) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013356-A1 | TRYCYCLIC COMPOUNDS AS PROSTAGLANDIN I2 RECEPTOR AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-02 | — | — | WO | disclosed |
| EP-0771196-A4 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1997-09-03 | — | — | EP | disclosed |
| EP-0771196-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996007405-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |