Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25838487 | 0.96 | HSD17B10 (0.32) | HSD17B10PRMT5WDR77 | |
| SCHEMBL30491327 | 0.88 | HTR1A (0.31) | PRMT5WDR77 | |
| SCHEMBL25838324 | 0.86 | LMNA (0.40) | — | |
| SCHEMBL25838489 | 0.83 | — | — | |
| SCHEMBL25838326 | 0.83 | SPR (0.33) | — | |
| SCHEMBL25838184 | 0.81 | ADRA1A (0.31) | — | |
| SCHEMBL25260039 | 0.80 | MAP3K12 (0.37) | — | |
| SCHEMBL30068714 | 0.80 | MAP3K12 (0.37) | — | |
| SCHEMBL25299916 | 0.80 | MAP3K12 (0.37) | — | |
| SCHEMBL25838331 | 0.79 | PRMT5 (0.32) | HSD17B10PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |