Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 10/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | JAK2 | O60674 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584595 | 0.92 | MEN1 (0.34) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2579815 | 0.89 | — | — | |
| SCHEMBL4520455 | 0.88 | MEN1 (0.34) | NTRK1MEN1KMT2AJAK2 | |
| SCHEMBL4520448 | 0.88 | MEN1 (0.34) | NTRK1MEN1KMT2AJAK2 | |
| SCHEMBL2578036 | 0.87 | — | — | |
| SCHEMBL4513904 | 0.86 | MEN1 (0.37) | NTRK1MEN1KMT2AATMHCRTR2 | |
| SCHEMBL4513907 | 0.86 | MEN1 (0.37) | NTRK1MEN1KMT2AATMHCRTR2 | |
| SCHEMBL2585816 | 0.84 | RIPK1 (0.37) | NTRK1KMT2AJAK2 | |
| SCHEMBL2585729 | 0.84 | FFAR2 (0.35) | — | |
| SCHEMBL2581259 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |