Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585816 | 0.90 | RIPK1 (0.37) | FFAR2RIPK1CALCRL | |
| SCHEMBL4511992 | 0.87 | FFAR2 (0.33) | FFAR2RIPK1 | |
| SCHEMBL4511999 | 0.87 | FFAR2 (0.33) | FFAR2RIPK1 | |
| SCHEMBL2581022 | 0.85 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL2584839 | 0.85 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL4505431 | 0.84 | FFAR2 (0.40) | FFAR2RIPK1P2RX7 | |
| SCHEMBL4505434 | 0.84 | FFAR2 (0.40) | FFAR2RIPK1P2RX7 | |
| SCHEMBL2579815 | 0.84 | — | — | |
| SCHEMBL2584595 | 0.84 | MEN1 (0.34) | FFAR2 | |
| SCHEMBL2583865 | 0.84 | NTRK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |