Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585729 | 0.90 | FFAR2 (0.35) | RIPK1CALCRLFFAR2 | |
| SCHEMBL2588030 | 0.88 | FFAR2 (0.39) | RIPK1CALCRLALDH1A1FFAR2 | |
| SCHEMBL4514302 | 0.88 | RIPK1 (0.37) | RIPK1OPRK1CALCRLALDH1A1DRD4 | |
| SCHEMBL4514297 | 0.88 | RIPK1 (0.37) | RIPK1OPRK1CALCRLALDH1A1DRD4 | |
| SCHEMBL2584595 | 0.86 | MEN1 (0.34) | ALDH1A1FFAR2KMT2A | |
| SCHEMBL4514257 | 0.86 | RIPK1 (0.41) | RIPK1OPRK1ALDH1A1FFAR2KMT2A | |
| SCHEMBL4514259 | 0.86 | RIPK1 (0.41) | RIPK1OPRK1ALDH1A1FFAR2KMT2A | |
| SCHEMBL2583865 | 0.84 | NTRK1 (0.34) | KMT2AJAK2NTRK1 | |
| SCHEMBL3617782 | 0.82 | FFAR2 (0.35) | FFAR2 | |
| SCHEMBL2583127 | 0.82 | FFAR2 (0.35) | FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |