Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 12/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 9/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2583870 | 1.00 | NTRK1 (0.33) | NTRK1MEN1KMT2AHCRTR2JAK2 | |
| SCHEMBL2584598 | 0.92 | MEN1 (0.35) | MEN1KMT2AHCRTR2 | |
| SCHEMBL2584599 | 0.92 | MEN1 (0.35) | MEN1KMT2AHCRTR2 | |
| SCHEMBL2579819 | 0.89 | — | — | |
| SCHEMBL2579817 | 0.89 | — | — | |
| SCHEMBL2578038 | 0.87 | PKM (0.30) | — | |
| SCHEMBL2578040 | 0.87 | PKM (0.30) | — | |
| SCHEMBL2585817 | 0.84 | RIPK1 (0.40) | HCRTR2RIPK1ALDH1A1 | |
| SCHEMBL2585819 | 0.84 | RIPK1 (0.40) | HCRTR2RIPK1ALDH1A1 | |
| SCHEMBL4520455 | 0.83 | MEN1 (0.34) | NTRK1MEN1KMT2AJAK2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |