Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 8/20 | 0.32 |
| ▸ | MC1R | Q01726 | 2/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584599 | 1.00 | MEN1 (0.35) | MEN1KMT2AHCRTR2KDM4EMC4R | |
| SCHEMBL2583870 | 0.92 | NTRK1 (0.33) | MEN1KMT2AHCRTR2 | |
| SCHEMBL2583867 | 0.92 | NTRK1 (0.33) | MEN1KMT2AHCRTR2 | |
| SCHEMBL2579819 | 0.89 | — | — | |
| SCHEMBL2579817 | 0.89 | — | — | |
| SCHEMBL2578040 | 0.87 | PKM (0.30) | — | |
| SCHEMBL2578038 | 0.87 | PKM (0.30) | — | |
| SCHEMBL2585819 | 0.86 | RIPK1 (0.40) | HCRTR2KDM4EFFAR2 | |
| SCHEMBL2585817 | 0.86 | RIPK1 (0.40) | HCRTR2KDM4EFFAR2 | |
| SCHEMBL4510749 | 0.83 | MEN1 (0.36) | MEN1KMT2AKDM4EMC4RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |