Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CEL | P19835 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119467 | 0.89 | ALDH1A1 (0.59) | ALDH1A1POLBKDM4ECYP3A4SLC6A2 | |
| SCHEMBL19860937 | 0.83 | LTA4H (0.46) | ALDH1A1NPC1RAB9ALTA4HHRH3 | |
| SCHEMBL18867753 | 0.83 | LTA4H (0.46) | ALDH1A1NPC1RAB9ALTA4HHRH3 | |
| SCHEMBL18867775 | 0.83 | LTA4H (0.46) | ALDH1A1NPC1RAB9ALTA4HHRH3 | |
| SCHEMBL19860836 | 0.83 | LTA4H (0.46) | ALDH1A1NPC1RAB9ALTA4HHRH3 | |
| SCHEMBL13504117 | 0.79 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9AHRH3CYP3A4 | |
| SCHEMBL894700 | 0.79 | GBA1 (0.66) | ALDH1A1HRH3CYP3A4SLC6A4KCNH2 | |
| SCHEMBL3130172 | 0.79 | ALDH1A1 (0.51) | ALDH1A1POLBCYP3A4SLC6A2SLC6A4 | |
| SCHEMBL21622788 | 0.79 | MAOB (0.55) | ALDH1A1NPC1RAB9APOLBCYP3A4 | |
| SCHEMBL7157755 | 0.79 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218547-A1 | CHEMICAL COMPOSITION | THE JOHN HOPKINS UNIVERSITY | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218547-A1 | CHEMICAL COMPOSITION | NDUFA10, NDUFA3, NDUFB10 | ALDH1A1 433/4885NPC1 1524/4885RAB9A 1492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.