SCHEMBL25839203

SCHEMBL25839203

CCCNC(=O)CCCOc1cc(C(=O)NCC(C)(C)COC)cc(C(=O)NCC(C)(C)COC)c1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
CNR1 P21554 15/20 0.44
CNR2 P34972 14/20 0.44
SLC6A5 Q9Y345 1/20 0.40
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26047672 0.76 HPGD (0.47) MEN1HPGDKMT2ACNR1CNR2
SCHEMBL25850543 0.74 CNR1 (0.44) CNR1CNR2
SCHEMBL25849004 0.72 NPC1 (0.33) MEN1KMT2ACNR1CNR2MAPT
SCHEMBL13498639 0.71 TSHR (0.71) MEN1HPGDKMT2ACNR1SMN1; SMN2
SCHEMBL26721862 0.70 NPC1 (0.52) MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL25843185 0.69 FAAH (0.53) MEN1KMT2ACNR1CNR2
SCHEMBL25835758 0.69 CNR1 (0.51) MEN1KMT2ACNR1CNR2MAPT
SCHEMBL26035275 0.67 CNR1 (0.39) MEN1KMT2ACNR1CNR2MAPT
SCHEMBL26035258 0.67 CNR1 (0.38) MEN1KMT2ACNR1CNR2MAPT
SCHEMBL25548847 0.66 CASP2 (0.47) MEN1KMT2ACNR1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 MEN1 4753/4885HPGD 2974/4885KMT2A 1603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.