SCHEMBL26035258

SCHEMBL26035258

Bc1cc(C(=O)NCC(C)(C)COCC(C)(C)CC(=O)NCC(C)(C)COCC(C)(C)CNC(=O)CCCCCCCCCCCCCCC)cc(C(=O)NCC(C)(C)COCC(C)(C)CC(=O)NCC(C)(C)COCC(C)(C)CNC(=O)CCCCCCCCCCCCCCC)c1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.38
CNR2 P34972 5/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FAAH O00519 2/20 0.36
EPHX2 P34913 4/20 0.35
TRPV1 Q8NER1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850543 0.85 CNR1 (0.44) CNR1CNR2TRPV1
SCHEMBL26035275 0.84 CNR1 (0.39) CNR1CNR2MEN1ALDH1A1MAPT
SCHEMBL24341855 0.81 FAAH (0.44) CNR1CNR2MEN1KMT2AFAAH
SCHEMBL25850206 0.79 FAAH (0.43) CNR1CNR2FAAH
SCHEMBL21096814 0.78 FAAH (0.46) CNR1CNR2MEN1KMT2AFAAH
SCHEMBL26048828 0.77 CNR1 (0.38) CNR1CNR2TRPV1
SCHEMBL25849437 0.75 FAAH (0.43) CNR1CNR2FAAHEPHX2
SCHEMBL26034080 0.74 FAAH (0.47) CNR1CNR2MEN1KMT2AFAAH
SCHEMBL25848473 0.74 NOD1 (0.40) FAAH
SCHEMBL24340612 0.71 FAAH (0.39) CNR1CNR2FAAHEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 CNR1 4167/4885CNR2 4501/4885MEN1 4828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.