Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 3/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.48 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.48 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24774075 | 0.87 | OPRD1 (0.53) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL25774591 | 0.87 | OPRD1 (0.53) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL25148131 | 0.87 | OPRD1 (0.53) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL24774070 | 0.85 | OPRD1 (0.53) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL24760306 | 0.85 | OPRD1 (0.53) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL25046490 | 0.83 | OPRD1 (0.49) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL24760230 | 0.83 | CTSS (0.55) | OPRD1OPRM1OPRK1CTSSCTSL | |
| SCHEMBL15806582 | 0.81 | OPRD1 (0.51) | PSMB5OPRD1OPRM1OPRK1CTSB | |
| SCHEMBL25148144 | 0.81 | FAAH (0.56) | PSMB5OPRD1OPRM1CTSB | |
| SCHEMBL23937555 | 0.80 | CTSS (0.55) | OPRD1OPRM1OPRK1CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137026-A1 | CAMPTOTHECIN ANALOGS CONJUGATED TO A GLUTAMINE RESIDUE IN A PROTEIN, AND THEIR USE | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-20 | — | — | WO | disclosed |