SCHEMBL25839726

SCHEMBL25839726

CCCC(=O)N[C@H]1CO[C@H](COC(=O)c2cccnc2)[C@@H](O)[C@@H]1O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ LMNA P02545 4/20 0.43
▸ KMT2A Q03164 5/20 0.42
▸ MEN1 O00255 3/20 0.42
▸ MAPT P10636 3/20 0.41
▸ ALDH1A1 P00352 3/20 0.40
▸ HPGD P15428 1/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ NAE1 Q13564 1/20 0.39
▸ UBA3 Q8TBC4 1/20 0.39
▸ BCHE P06276 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.38
▸ BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25835051 0.82 L3MBTL1 (0.46) L3MBTL1LMNAKMT2AMEN1MAPT
SCHEMBL25835954 0.81 L3MBTL1 (0.45) L3MBTL1LMNAKMT2AMEN1MAPT
SCHEMBL21138642 0.81 L3MBTL1 (0.45) L3MBTL1LMNAKMT2AMEN1MAPT
SCHEMBL21138290 0.79 BCHE (0.42) L3MBTL1LMNAKMT2AMAPTALDH1A1
SCHEMBL26290975 0.79 MAPT (0.50) L3MBTL1LMNAKMT2AMEN1MAPT
SCHEMBL21137909 0.77 PYGB (0.41) L3MBTL1
SCHEMBL21138289 0.74 BCHE (0.37) LMNAKMT2AMEN1ALDH1A1BCHE
SCHEMBL23104782 0.74 PYGB (0.39) L3MBTL1
SCHEMBL25836026 0.73 PYGB (0.33) L3MBTL1KMT2AMEN1MAPTALDH1A1
SCHEMBL26290435 0.72 MAPT (0.50) L3MBTL1LMNAKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA L3MBTL1 4558/4885LMNA 2743/4885KMT2A 4171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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