SCHEMBL21138642

SCHEMBL21138642

CCCC(=O)N[C@H]1C(C)O[C@H](COC(=O)c2cccnc2)[C@@H](O)[C@@H]1O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ LMNA P02545 3/20 0.43
▸ MAPT P10636 4/20 0.41
▸ TDP1 Q9NUW8 2/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ ALDH1A1 P00352 5/20 0.40
▸ KMT2A Q03164 4/20 0.40
▸ MEN1 O00255 3/20 0.40
▸ BLM P54132 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ TP53 P04637 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25835051 0.91 L3MBTL1 (0.46) L3MBTL1LMNAMAPTTDP1MAPK1
SCHEMBL26290435 0.83 MAPT (0.50) L3MBTL1LMNAMAPTTDP1MAPK1
SCHEMBL21137880 0.81 HK1 (0.39) L3MBTL1LMNAMAPTMAPK1ALDH1A1
SCHEMBL25839726 0.81 L3MBTL1 (0.45) L3MBTL1LMNAMAPTTDP1ALDH1A1
SCHEMBL25835954 0.81 L3MBTL1 (0.45) L3MBTL1LMNAMAPTTDP1MAPK1
SCHEMBL21138213 0.79 LMNA (0.37) L3MBTL1LMNATDP1ALDH1A1KMT2A
SCHEMBL21137906 0.77 PYGB (0.44) L3MBTL1MAPK1ALDH1A1
SCHEMBL18365284 0.76 HK1 (0.49) —
SCHEMBL5981575 0.76 MAPT (0.51) L3MBTL1LMNAMAPTTDP1MAPK1
SCHEMBL30681167 0.76 MAPT (0.51) L3MBTL1LMNAMAPTTDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA L3MBTL1 3561/4885LMNA 2632/4885MAPT 3677/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA L3MBTL1 3561/4885LMNA 2632/4885MAPT 3677/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA L3MBTL1 4558/4885LMNA 2743/4885MAPT 2761/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA L3MBTL1 4558/4885LMNA 2743/4885MAPT 2761/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA L3MBTL1 4558/4885LMNA 2743/4885MAPT 2761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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