SCHEMBL25839769

SCHEMBL25839769

COCCCC(=O)NCC(C)(C)COCC(C)(C)COc1ccc(-c2nnc(S(C)(=O)=O)o2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 5/20 0.38
TSHR P16473 2/20 0.38
ALOX15 P16050 2/20 0.38
HPGD P15428 4/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TP53 P04637 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
SMPD1 P17405 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HTT P42858 1/20 0.34
KDM4E B2RXH2 1/20 0.34
POLB P06746 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PKM P14618 1/20 0.34
LMNA P02545 1/20 0.33
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26036521 0.86 HPGD (0.40) L3MBTL1MAPTTSHRALOX15HPGD
SCHEMBL25840398 0.79 MAPT (0.32) L3MBTL1MAPTTSHRALOX15
SCHEMBL25834990 0.73 ATM (0.41) MAPTTSHRALOX15HPGDMEN1
SCHEMBL25840443 0.72
SCHEMBL25839775 0.70 RECQL (0.47) MAPTTSHRALOX15HPGDTP53
SCHEMBL24340831 0.70 CA12 (0.56) MAPTHPGDTP53ALDH1A1HTT
SCHEMBL24340791 0.70 MTNR1A (0.51) L3MBTL1MAPTTSHRALOX15HPGD
SCHEMBL25834992 0.68 ALDH1A1 (0.46) MAPTTSHRHPGDHDAC8SMPD1
SCHEMBL31671377 0.68 ALDH1A1 (0.40) MAPTTSHRALOX15HPGDTP53
SCHEMBL25850181 0.68 NPC1 (0.61) MAPTMEN1KMT2ATP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 L3MBTL1 1095/4885MAPT 3973/4885TSHR 1324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.