SCHEMBL25840398

SCHEMBL25840398

CCCCCCCCC(CCCCCC)C(=O)NCC(C)(C)COC(C)(C)CNC(=O)c1cc(OCCCC(=O)NCC(C)(C)COCC(C)(C)COc2ccc(-c3nnc(S(C)(=O)=O)o3)cc2)cc(C(=O)NCC(C)(C)COP)c1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26036063 0.85 MAPT (0.37) MAPTALOX15TSHRL3MBTL1
SCHEMBL25836356 0.80 MAPT (0.37) MAPTALOX15TSHR
SCHEMBL25839769 0.79 L3MBTL1 (0.41) MAPTALOX15TSHRL3MBTL1
SCHEMBL25836233 0.70 MAPT (0.39) MAPTALOX15TSHR
SCHEMBL25836103 0.70 MAPT (0.39) MAPTALOX15TSHR
SCHEMBL25840379 0.69 CNR1 (0.33)
SCHEMBL26032102 0.69 MAPT (0.38) MAPTALOX15TSHR
SCHEMBL26033614 0.69 MAPT (0.38) MAPTALOX15TSHR
SCHEMBL26036521 0.69 HPGD (0.40) MAPTALOX15TSHRL3MBTL1
SCHEMBL26035286 0.66 SLC6A5 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 MAPT 3973/4885ALOX15 1471/4885TSHR 1324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.