Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22037150 | 1.00 | ERCC5 (0.36) | ERCC5FEN1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL23969673 | 0.78 | ATM (0.37) | SMN1; SMN2HPGDKMT2AALDH1A1GAA | |
| SCHEMBL16728770 | 0.77 | MAOA (0.38) | ERCC5FEN1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL23334259 | 0.76 | ERCC5 (0.40) | ERCC5FEN1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL18790936 | 0.75 | HPGD (0.41) | ERCC5FEN1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL22111212 | 0.75 | HPGD (0.41) | ERCC5FEN1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL20416465 | 0.74 | KMT2A (0.36) | ERCC5FEN1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL24969789 | 0.73 | ERCC5 (0.33) | ERCC5FEN1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL12986905 | 0.72 | MAOA (0.36) | ERCC5FEN1MAOAMAOBSMN1; SMN2 | |
| SCHEMBL23334427 | 0.71 | ERCC5 (0.39) | ERCC5FEN1SMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230309396-A1 | Host Materials for Electroluminscent Devices | UNIVERSAL DISPLAY CORPORATION | 2023-09-28 | — | — | US | disclosed |
| US-11706980-B2 | Host materials for electroluminescent devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11706980-B2 | Host materials for electroluminescent devices | CRHR1, CRHR2, CRH | ERCC5 757/4885FEN1 2474/4885MAOA 2628/4885 |
| US-20230309396-A1 | Host Materials for Electroluminscent Devices | CRHR1, CRHR2, CRH | ERCC5 778/4885FEN1 2392/4885MAOA 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.