Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25840308 | 0.82 | KCNN4 (0.44) | KMT2AMAPTMEN1HTTMAPK1 | |
| SCHEMBL13626314 | 0.80 | MEN1 (0.49) | KMT2ASMN1; SMN2MAPTMEN1HTT | |
| SCHEMBL8384266 | 0.72 | KDM4E (0.53) | KMT2AMAPTMEN1TSHRKDM4E | |
| SCHEMBL13427572 | 0.70 | KCNN4 (0.61) | KMT2ASMN1; SMN2MAPTMEN1HTT | |
| SCHEMBL8920573 | 0.70 | RAB9A (0.49) | KMT2ASMN1; SMN2MAPTMEN1HTT | |
| Acetone SCHEMBL27946364 | 0.69 | CES2 (0.58) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL9768982 | 0.68 | KMT2A (0.48) | KMT2ASMN1; SMN2MAPTMEN1HTT | |
| SCHEMBL20312568 | 0.68 | MEN1 (0.48) | KMT2ASMN1; SMN2MAPTMEN1HTT | |
| SCHEMBL25460835 | 0.68 | NPC1 (0.44) | KMT2ASMN1; SMN2MAPTMEN1HTT | |
| SCHEMBL1851604 | 0.68 | PDE2A (0.48) | HTTLMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125825-A1 | ANTICORONVIRAL COMPOUNDS AND COMPOSITIONS AND USES THEREOF | SHANGHAI CUREGENE PHARMACEUTICAL CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |