Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920378 | 0.86 | HTT (0.42) | KMT2ATAAR1HTTSMN1; SMN2TP53 | |
| SCHEMBL8920367 | 0.77 | ALDH1A1 (0.49) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL10767261 | 0.72 | USP2 (0.66) | RAB9AUSP2MEN1KMT2ATAAR1 | |
| SCHEMBL25840311 | 0.70 | KMT2A (0.44) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL13626314 | 0.70 | MEN1 (0.49) | RAB9AMEN1KMT2AL3MBTL1NPC1 | |
| Bromide SCHEMBL8121179 | 0.68 | USP2 (0.55) | RAB9AUSP2MEN1KMT2ATAAR1 | |
| SCHEMBL11684104 | 0.68 | USP2 (0.70) | RAB9AUSP2MEN1KMT2ATAAR1 | |
| SCHEMBL2309836 | 0.67 | USP2 (1.00) | RAB9AUSP2MEN1KMT2ATAAR1 | |
| Acetic Acid SCHEMBL29241773 | 0.66 | LTA4H (0.56) | RAB9AUSP2MEN1KMT2ATAAR1 | |
| SCHEMBL11681426 | 0.65 | USP2 (0.66) | RAB9AUSP2MEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727998-A4 | OXAZOLES FOR TREATING CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORP (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0727998-A1 | OXAZOLES FOR TREATING CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013067-A1 | OXAZOLES FOR TREATING CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-18 | — | — | WO | disclosed |