Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25840797 | 0.83 | NPC1 (0.57) | NPC1RAB9APOLBSMN1; SMN2MEN1 | |
| SCHEMBL25840791 | 0.81 | CA12 (0.46) | NPC1RAB9APOLBSMN1; SMN2MEN1 | |
| SCHEMBL25840787 | 0.81 | SMN1; SMN2 (0.57) | POLBSMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL25840803 | 0.81 | ALDH1A1 (0.59) | NPC1RAB9APOLBSMN1; SMN2MEN1 | |
| SCHEMBL23328392 | 0.79 | EPHX2 (0.64) | NPC1RAB9AMEN1KMT2ACNR1 | |
| SCHEMBL5851707 | 0.78 | NPC1 (0.68) | NPC1RAB9APOLBSMN1; SMN2MEN1 | |
| SCHEMBL12018601 | 0.77 | NPC1 (0.57) | NPC1RAB9APOLBSMN1; SMN2MEN1 | |
| SCHEMBL1275920 | 0.77 | ALDH1A1 (0.70) | NPC1RAB9APOLBSMN1; SMN2MEN1 | |
| SCHEMBL11845544 | 0.77 | LMNA (0.58) | NPC1RAB9APOLBSMN1; SMN2MEN1 | |
| SCHEMBL24917489 | 0.77 | NPC1 (0.66) | NPC1RAB9APOLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11701333-B2 | Antibacterial compounds | Kent Innovation & Enterprise (GB) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11701333-B2 | Antibacterial compounds | ARF1, ARL1, TLR1 | NPC1 407/4885RAB9A 1656/4885POLB 3462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.