SCHEMBL25843067

SCHEMBL25843067

C=C1N=C(ON)C=CN1[C@H]1CC(O)[C@@H](COP(=O)(O)O)O1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TYMS P04818 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25843064 0.84 ADRB1 (0.40) —
SCHEMBL25842997 0.83 TYMS (0.36) TYMS
SCHEMBL25843066 0.81 FBP1 (0.46) —
SCHEMBL25843121 0.79 TYMS (0.44) TYMS
SCHEMBL146996 0.75 P2RY2 (0.42) TYMS
SCHEMBL19412412 0.75 P2RY2 (0.42) TYMS
SCHEMBL25842996 0.75 FBP1 (0.47) —
SCHEMBL22765896 0.70 TYMS (0.50) TYMS
SCHEMBL4321066 0.70 TYMS (0.53) TYMS
SCHEMBL22990560 0.69 POLB (0.62) TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219994-A1 MODIFIED NUCLEOSIDE AND SYNTHESIS METHOD THEREFOR Stemirna Therapeutics Co., Ltd. (CN) 2023-07-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219994-A1 MODIFIED NUCLEOSIDE AND SYNTHESIS METHOD THEREFOR RNMT, RNGTT, BCDIN3D TYMS 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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